![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/12/PF-06426779-is-a-Selective-IRAK4-inhibitor-2020-12-09.jpg)
IRAK4 (interleukin-1 receptor-associated kinase 4) is a protein kinase in the IRAK family. Specifically, IRAK-4 is relevant to signal transduction…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/09/SP-100030-is-a-Potent-NF-κB-and-Activator-Protein-1-AP-1-Inhibitor-2020-10-01.jpg)
Nuclear factor-κB (NF-κB) represents a family of inducible transcription factors. The transcription factor NF-κB regulates multiple aspects of innate and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/06/R243-Inhibits-CCL1-CCR8-Interaction-with-Antinociceptive-and-Anti-inflammatory-Effects-2020-06-17-1.jpg)
Chemokine (C-C motif) receptor 8, also known as CCR8, is a protein encoded by the CCR8 gene in the human…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/12/CU-T12-9-is-a-Specific-TLR1-2-Agonist-2020-01-01.jpg)
Toll-like receptors belong to a family of pattern recognition receptors, regulate innate immunity and subsequent adaptive immune responses. TLRs can…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/12/Selgantolimod-is-an-Orally-Active-and-Selectiv-TLR8-Agonist-for-HBV-and-HIV-for-Treatment-2019-12-29.jpg)
Toll-like receptors (TLRs) are type I membrane glycoproteins. They contain intracellular Toll–IL-1 receptor homology (TIR) domains. TLRs recognize a wide…