Toll-like receptors (TLRs) play a crucial role in the innate immune system by recognizing pathogen-related molecular patterns from various microorganisms. Specifically, TLRs signal by recruiting specific adaptor molecules, leading to…
Abdominal aortic aneurysm (AAA) is a localized enlargement of the abdominal aorta, larger than normal. It commonly causes no symptoms, but sometimes it has symptoms through pushing on the abdomen.…
EGFR (Epidermal Growth Factor Receptor) is a receptor on the surface of cells which is expressed in many normal epithelial tissues, including skin. The EGFR signaling pathway plays an important…
SB 203580 was identified as a selective p38 MAPK (p38 mitogen-activated protein kinases) inhibitor over 20 years ago. And it shows more than 100-fold selectivity over Akt (PKB), LCK, and…