Otaplimastat (SP-8203) is a MMP Inhibitor
Oxidative stress is a major cause of neuronal cell death, including ischemic brain injury. Cell culture models and animal experiments indicated neuronal cell death can produce reactive oxygen species such…
CMC2.24 is an Orally Active Tricarbonylmethane Agent
RAS is the name of a series of related proteins commonly expressed in all cell lineages and organs. Specifically, RAS is a prototype member of the Ras protein superfamily. All…
PD-166793 is a Selective and Orally Active MMP Inhibitor
Matrix metalloproteinases (MMPs) are a protein family of zinc-containing endopeptidases. Especially, MMPs are essential in (neuro)inflammation. MMPs act as enzymes capable of catalyzing the hydrolysis of collagen. MMP-3 binds to…
CP-471474 is an Orally Active and pan MMP Inhibitor
Matrix metallopeptidases (MMPs) are a kind of metalloproteinase which belongs to calcium-dependent zinc endopeptidase. Specifically, these enzymes can degrade all kinds of extracellular matrix proteins, but they can also process…