Dopamine D1 receptors are important G protein-coupled receptors in the central nervous system (CNS). They activate different effectors through G protein coupling and interact with the neurotransmitter dopamine to signal.…
Striatal-enriched protein tyrosine phosphatase (STEP) is a CNS-rich protein associated with a variety of neurological and neuropsychiatric disorders. Firstly, it is expressed exclusively in the central nervous system. Then, it…
Histamine receptors are a type of G protein-coupled receptor (GPCR), including four subtypes: H1, H2, H3, and H4 receptors. They have different functions. For example, the H1 receptor regulates circadian…
Sodium channels are integral membrane proteins that form ion channels and conduct sodium ions (Na+) through the plasma membrane. These channels pass through three different states, which are resting state,…