Elvitegravir is an HIV Integrase Inhibitor for HIV Research
Retrovirus is a virus that inserts a DNA copy of its RNA genome into the DNA of the host cell it invades, thereby changing the genome of that cell. After…
Retrovirus is a virus that inserts a DNA copy of its RNA genome into the DNA of the host cell it invades, thereby changing the genome of that cell. After…
Reverse transcriptases (RTs) are enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. Reverse transcriptases (RTs) use an RNA template and a short…
Capsid (CA) protein is a major virion-constituent of all retroviruses including human immunodeficiency virus type 1 (HIV-1). It is essential for early and late phases in the viral replication cycle.…
HIV is a virus that affects the immune system. HIV infects important cells in the human immune system, such as helper T cells (especially CD4+T cells), macrophages, and dendritic cells.…
HIV-1 integrase (IN) is an enzyme responsible for integrating the viral DNA copy of the viral RNA genome into the host chromatin. Specifically, IN is one of the main anti-virus…
The human immunodeficiency virus (HIV) is a retrovirus. It can cause acquired immunodeficiency syndrome (AIDS), and weaken people's defense against many infections and some types of cancer. This virus kills…
HIV protease, a homodimeric aspartyl protease, is an essential component of the Human Immunodeficiency Virus genome. HIV protease is responsible for cleaving the Gag and Gag-Pol polyproteins in a late…
HIV protease is a homodimeric aspartyl protease. It is worth noting that, HIV protease is crucial for the viral life-cycle. Specifically, HIV protease cleaves proviral polyproteins, hence creates mature protein…
Topoisomerase I and II are essential enzymes in the regulation of DNA topology and super coiling. They are crucial for transcription and replication. Topoisomerase I (topo I) breaks one of…
CXCR-4 is an α-chemokine receptor specific for SDF-1, which is a molecule with the strong chemotactic activity of lymphocytes. Specifically, CXCR-4 is a receptor of stromal cell-derived factor-1 α and…