Otaplimastat (SP-8203) is a MMP Inhibitor
Oxidative stress is a major cause of neuronal cell death, including ischemic brain injury. Cell culture models and animal experiments indicated neuronal cell death can produce reactive oxygen species such…
Oxidative stress is a major cause of neuronal cell death, including ischemic brain injury. Cell culture models and animal experiments indicated neuronal cell death can produce reactive oxygen species such…
Retinoic acid (RA) is a metabolite of vitamin A1, which can regulate the function of vitamin A1 required for growth and development. Specifically, the antitumor effect of retinoids is attributed…
SARS-CoV is the coronavirus (CoV) that causes severe acute respiratory syndrome (SARS), including not only SARS, but also Middle East respiratory syndrome (MERS) and SARS-CoV-2 (the cause of COVID-19). The…
NLRX1 is a highly conserved nucleotide-binding domain (NBD) and a member of the leucine-rich repeat (LRR) family (NLR). Specifically, NLRX1 is an intracellular protein that plays a role in the…
Dopamine Receptors are a class of G protein-coupled receptors, widely exist in the brain. There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The…
Gingipains are a family of proteases secreted by Porphyromonas gingivalis. Members of gingipains (family C25) strictly cleave peptide bonds with either Arg-Xaa or Lys-Xaa at the cleavage site, and Arg-gingipain…
Dopamine (DA) is a catecholamine neurotransmitter. Dopamine participates in the regulation of nervous system movement and neuroendocrine. Besides, many studies have found that dopamine participates in the regulation of immune…