![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/10/Varespladib-LY315920-is-a-Selective-Group-IIAs-PLA2-Inhibitor-2021-10-28.jpg)
Phospholipases A2 (PLA2s) are enzymes that cleave fatty acid in position two of phospholipids, hydrolyzing the bond between the second…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/GSK620-is-a-Potent-and-Orally-Active-pan-BET-BD2-Inhibitor-2020-01-08.jpg)
The therapeutic potential of extra terminal domain inhibitor (iBET) has increasing studies both in oncology and immunoinflammatory. Moreover, iBETs are…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/09/RBN012759-is-a-Selective-and-Orally-Active-Inhibitor-of-PARP14-2020-10-14.jpg)
Poly (ADP ribose) polymerase (PARP) is a family of proteins involved in many cellular processes, such as DNA repair, genomic…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/09/PF06650833-is-an-Orally-Active-IRAK4-Inhibitor-2020-09-15.jpg)
Interleukin-1 receptor-associated kinase 4 (IRAK4) is a key node in innate inflammatory signaling. It is also directly downstream of the…
Tumor angiogenesis plays an essential role in carcinogenesis, cancer progression, and metastasis. The inflammation is a key feature of the…