MSX-122 is a Partial Antagonist of CXCR4
Chemokines and their receptors participate a variety of immune responses to infection, inflammation, and tissue repair. Among them, CXCR4 is a chemokine receptor that has one known natural ligand, CXCL12…
Chemokines and their receptors participate a variety of immune responses to infection, inflammation, and tissue repair. Among them, CXCR4 is a chemokine receptor that has one known natural ligand, CXCL12…
NF-κB is a transcription factor with heterodimer or homodimer form of rel family proteins such as RelA (p65), RelB, cRel, p50 and p52. NF-κB binds to inhibitory κB (IκB) proteins…
As we all know, Colitis is a kind of inflammatory diseases. Sometimes it is acute and long term, makes patients painful. EP4 receptor (Prostaglandin E2 receptor 4) is a prostaglandin…
In the blog “Network of Cancer Research”, we have introduced Ralimetinib with anti-tumor activity. In fact, the scientists identified Ralimetinib that has excellent anti-inflammatory properties, firstly. Firstly, let's review the…
NF-κBs are homo- or heterodimers of the structurally related subunits p65 (RelA), RelB, cRel, p50 and p52. NF-κB plays a key role in regulating the immune response to infection. NFκBs…
Immunoproteasome plays a critical role in the immune system because it degrades intracellular proteins, for example, those of viral origin, into small proteins. Immunoproteasome is abundantly expressed in immune cells.…