![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/KMH-233-is-a-Reversible-and-Selective-LAT1-Inhibitor-2020-01-18.jpg)
Amino acids are essential for protein synthesis, they are supporting cell growth, and metabolism. System L belongs to the family…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/12/CB-5083-is-a-Selective-and-Orally-Bioavailable-p97-Inhibitor-2020-12-17.jpg)
The AAA+ ATPase p97 is essential to a wide range of cellular functions. The p97 acts downstream from ubiquitin signaling…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/iGOT1-01-is-a-Potent-Aspartate-Aminotransferase-1-GOT1-Inhibitor-2020-11-26.jpg){kind=spacer}
Glutamate-oxaloacetate transaminase (GOT) is a Pyr aldehyde phosphate-dependent enzyme. Specifically, it exists in the form of cytoplasm and mitochondria, GOT1,…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/09/CH-0793076-a-Hexacyclic-Camptothecin-Analog-Inhibits-DNA-Topoisomerase-I-2020-09-26.jpg)
CPT-11 and Topotecan are two potent DNA topoisomerase I inhibitors in clinical. CPT-11 is the prodrug of SN-38. Topotecan is…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/08/SC-58125-is-a-Potent-and-Selective-COX-2-Inhibitor-2020-09-05.jpg)
Nonsteroidal anti-inflammatory agents (NSAIDs) are useful for the treatment of inflammatory diseases. In particular, NSAIDs inhibit the enzyme cyclooxygenase (COX),…