Tumor necrosis factor (TNF) is a cytokine belonging to a family of trimeric proteins. This factor acts as a key…
Adenosine is an endogenous purine nucleoside present in every cell of the human body. Four distinct adenosine receptor subtypes are…
Toll-like receptors belong to a family of pattern recognition receptors, regulate innate immunity and subsequent adaptive immune responses. TLRs can…
Toll-like receptors (TLRs) are type I transmembrane proteins. They can recognize pathogen-derived macromolecules, thereby playing a key role in the…
Motolimod (VTX-2337) is a selective Toll-like receptor (TLR) 8 agonist. In vitro, HEK293 cells with various human TLRs, only Motolimod activates…