![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/02/UCB-9260-Inhibits-TNF-Signalling-by-Stabilising-an-Asymmetric-form-of-the-Trimer-2021-02-10.jpg)
Tumor necrosis factor (TNF) is a cytokine belonging to a family of trimeric proteins. This factor acts as a key…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/01/GS-6201-is-a-Selective-Adenosine-A2B-Receptor-Antagonist-2020-01-27.jpg)
Adenosine is an endogenous purine nucleoside present in every cell of the human body. Four distinct adenosine receptor subtypes are…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/12/CU-T12-9-is-a-Specific-TLR1-2-Agonist-2020-01-01.jpg)
Toll-like receptors belong to a family of pattern recognition receptors, regulate innate immunity and subsequent adaptive immune responses. TLRs can…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/10/CU-CPT22-is-a-TLR1-TLR2-Complex-Inhibitor-2019-10-27.jpg)
Toll-like receptors (TLRs) are type I transmembrane proteins. They can recognize pathogen-derived macromolecules, thereby playing a key role in the…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/10/Motolimod-is-a-Selective-TLR8-Agonist-2019-10-25.jpg)
Motolimod (VTX-2337) is a selective Toll-like receptor (TLR) 8 agonist. In vitro, HEK293 cells with various human TLRs, only Motolimod activates…