ML 145 is a Selective GPR35 Antagonist
CXCL17 is a mucosal chemokine that associates with human diseases including idiopathic pulmonary fibrosis (IPF) and cancer. CXCL17 is an antimicrobial mucosal chemokine that may play a role in the…
CXCL17 is a mucosal chemokine that associates with human diseases including idiopathic pulmonary fibrosis (IPF) and cancer. CXCL17 is an antimicrobial mucosal chemokine that may play a role in the…
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase. Syk plays an important role in allergic diseases and inflammation. Thus, Syk is an attractive target for therapeutic kinase inhibitors. This…
In previous blogs, I have introduces several RIPK inhibitors, including RIP1 inhibitors RIPA-56, PK68, GSK547, GNE684, and GSK2982772. But the RIP2 inhibitors are lacked, today, I’d like to make up…
The innate immune system is a key driver of our immune response from birth. It provides an immediate response to foreign invaders. It comprises pattern recognition receptors (PRRs). Toll-like receptors…