Abelacimab (MAA868) is a Fully Human IgG1 mAb That Binds to Factor XI
Factor XI (FXI) is a serine protease that in humans is encoded by the F11 gene. FXI mainly exists in the liver and is present in the circulation as an…
Factor XI (FXI) is a serine protease that in humans is encoded by the F11 gene. FXI mainly exists in the liver and is present in the circulation as an…
Glucagon plays an important role in glucose metabolism. Upon hypoglycemia, pancreatic alpha cells can secrete glucagon which stimulates hepatic glucose production. However increased glucagon concentrations contribute to diabetic hyperglycemia. In…
Tau (Tubulin-associated unit) is a microtubule-associated protein (MAP) that is primarily present in axons. Besides, Tau is a multi-functional protein. Particularly, It takes part in the cross-linking and regulation of…
SARS-COV-2 is a positive-sense single-stranded RNA coronavirus. This virus can cause severe acute respiratory syndrome and spreads between people through aerosols and respiratory droplets. It broke out in early 2020,…
Melittin is the main component of bee venom and the main pain-causing substance that can cause allergic reactions. When injected into animals and humans Melittin causes nociception and activates pain…
eIF2 (eukaryotic initiation factor 2), an eukaryotic initiation factor, is an essential factor for protein synthesis. eIF2 mediates the binding of tRNAiMet to the ribosome in a GTP-dependent manner. And…
Nrf2 is a transcription factor, that regulates the expression of antioxidant proteins. Besides, Nrf2 protects against oxidative damage triggered by injury and inflammation. Importantly, NRF2 appears to participate in a…