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Tag: PDI

KSC-34 is a Site-Selective Inhibitor of PDIA1

2021-02-17 Edward Jenner

Proper folding of nascent proteins in the cell is accelerated by chaperones. They serve to stabilize protein domains and overall…

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Posted in: Immunology Filed under: PDI, PDIA1

PACMA 31 is an Irreversible and Orally Active Protein Disulfide Isomerase (PDI) Inhibitor

2020-12-08 Edward Jenner

Ovarian cancer is one of the leading causes of death in women with gynecological cancers in the United States. About…

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Posted in: Cancer Immunology Filed under: ER Stress, Low Toxicity, Ovarian Cancer, PDI
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