![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/02/Enpatoran-is-an-Orally-Active-and-Dual-TLR7-8-Inhibitor-2021-02-27.jpg)
Toll-like receptors 7 and 8 (TLR7/8) are receptors for single-stranded RNA that reside in the endosome. TLR8 mainly expresses in…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/MSC2360844-is-an-Orally-Active-and-Selective-PI3Kδ-Inhibitor-2020-11-07-1.jpg)
SLE is a complex autoimmune inflammatory disease that affects multiple organs with unpredictable flares. Autoantibody/antigen immune-complexes in turn can activate…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/05/3M-011-a-Cytokine-Inducer-is-a-Dual-TLR7-8-Agonist-2020-05-09.jpg)
3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer. Firstly, in B16-F10 melanoma cells, 3M-011 treatment can decrease…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/12/CU-T12-9-is-a-Specific-TLR1-2-Agonist-2020-01-01.jpg)
Toll-like receptors belong to a family of pattern recognition receptors, regulate innate immunity and subsequent adaptive immune responses. TLRs can…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/10/PF-4878691-is-a-Selective-TLR7-Agonist-with-HCV-Antiviral-Efficacy-2019-11-03.jpg)
Chronic hepatitis C (CHC) virus infection continues to be a significant health burden, and 2–3% of the global population infected…