Toll-like receptors 7 and 8 (TLR7/8) are receptors for single-stranded RNA that reside in the endosome. TLR8 mainly expresses in…
SLE is a complex autoimmune inflammatory disease that affects multiple organs with unpredictable flares. Autoantibody/antigen immune-complexes in turn can activate…
3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer. Firstly, in B16-F10 melanoma cells, 3M-011 treatment can decrease…
Toll-like receptors belong to a family of pattern recognition receptors, regulate innate immunity and subsequent adaptive immune responses. TLRs can…
Chronic hepatitis C (CHC) virus infection continues to be a significant health burden, and 2–3% of the global population infected…