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Tag: TYK

GDC-046 is a Selective and Orally Bioavailable TYK2 Inhibitor

2020-07-15 Edward Jenner

Psoriasis and inflammatory bowel diseases (IBD), both of them are chronic inflammatory diseases. The characterizes of Psoriasis are mainly red…

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Posted in: Inflammation Filed under: IL-12, JAK, STAT, TYK

BMS-986165 is a Highly Selective and Orally Active TYK2 Inhibitor for Autoimmune Diseases Treatment

2019-08-20 Edward Jenner

Janus kinases are non-receptor tyrosine kinases. In mammals, the family has four members, Jak1, Jak2, Jak3 and Tyrosine kinase 2…

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Posted in: Autoimmune Disorders, Psoriasis, Skin Inflammation, Systemic Lupus Erythematosus Filed under: IFN, TYK
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