BRD3308, a Highly Selective HDAC3 Inhibitor, Activates HIV-1 Transcription and Disrupts HIV-1 Latency

Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from an ε-N-acetyl-lysine amino acid on a histone. Specifically, selective HDAC inhibitors are as a potential anti latent…