PK68, a type II Inhibitor of RIPK1, Has potential to Treat Inflammatory Disorders and Cancer Metastasis
Necroptosis is a form of regulated necrosis controlled by receptor-interacting kinase 1 (RIPK1), RIPK3, and mixed lineage kinase domain-like protein (MLKL). Necroptosis closely associates with pathologies including inflammatory diseases, neurodegenerative…